AURKB, aurora kinase B, 9212

N. diseases: 161; N. variants: 3
Disease: MRSA - Methicillin resistant Staphylococcus aureus infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0343401
Disease: MRSA - Methicillin resistant Staphylococcus aureus infection
MRSA - Methicillin resistant Staphylococcus aureus infection 		0.020 Biomarker disease BEFREE Here, we report that the pyrazolopyridazine GW779439X sensitizes methicillin-resistant Staphylococcus aureus (MRSA) to various β-lactams through inhibition of the PASTA kinase Stk1. 30059625 2018
CUI: C0343401
Disease: MRSA - Methicillin resistant Staphylococcus aureus infection
MRSA - Methicillin resistant Staphylococcus aureus infection 		0.020 Biomarker disease BEFREE STK1, despite being nonessential protein for MRSA survival, it can serve as an important therapeutic agent for combination therapy. 28698584 2017