CD7, CD7 molecule, 924

N. diseases: 22; N. variants: 0
Disease: Leukemia, Myelocytic, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.030 Biomarker disease BEFREE Here, we show that expression of a CD7-directed CAR in CD7 gene-edited (CD7<sup>KO</sup>) T cells effectively eliminates CD7<sup>+</sup> AML cell lines, primary CD7<sup>+</sup> AML, and colony-forming cells but spares myeloid and erythroid progenitor cells and their progeny. 30391141 2019
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.030 GeneticVariation disease LHGDN Aberrant expression of CD7 in myeloblasts is highly associated with de novo acute myeloid leukemias with FLT3/ITD mutation. 18343790 2008
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.030 Biomarker disease BEFREE Five cases of ANLL which were positive with 4A antibody were selected and tested with Tp40 antibody, and only two were found to be positive. 1701841 1990