GPR50, G protein-coupled receptor 50, 9248

N. diseases: 31; N. variants: 4
Disease: Bipolar Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 GeneticVariation disease BEFREE To our knowledge this is the first association of rs1202874 with BD and is the second positive association at the GPR50 locus. 20371266 2010
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 Biomarker disease PSYGENET To our knowledge this is the first association of rs1202874 with BD and is the second positive association at the GPR50 locus. 20371266 2010
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 Biomarker disease PSYGENET The positional candidate approach showed an association between bipolar disorder and TRPM2 (21q22.3), GPR50 (Xq28), Citron (12q24), CHMP1.5 (18p11.2), GCHI (14q22-24), MLC1 (22q13), GABRA5 (15q11-q13), BCR (22q11), CUX2, FLJ32356 (12q23-q24), and NAPG (18p11). 17239033 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 Biomarker disease BEFREE Our choice of this gene for study was based on a previous report of an association of GPR50 with bipolar disorder and major depressive disorder. 18075476 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 Biomarker disease PSYGENET Our choice of this gene for study was based on a previous report of an association of GPR50 with bipolar disorder and major depressive disorder. 18075476 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 GeneticVariation disease BEFREE Recently an insertion/deletion polymorphism in GPR50, Delta502-505, was found to be associated with BP in a Scottish association sample (P=0.007). 17106423 2006
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 Biomarker disease PSYGENET Recently an insertion/deletion polymorphism in GPR50, Delta502-505, was found to be associated with BP in a Scottish association sample (P=0.007). 17106423 2006
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 GeneticVariation disease BEFREE These results suggest that GPR50(Delta502-505), or a variant in tight linkage disequilibrium with this polymorphism, is a sex-specific risk factor for susceptibility to bipolar disorder, and that other variants in the gene may be sex-specific risk factors in the development of schizophrenia. 15452587 2005
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.340 Biomarker disease PSYGENET These results suggest that GPR50(Delta502-505), or a variant in tight linkage disequilibrium with this polymorphism, is a sex-specific risk factor for susceptibility to bipolar disorder, and that other variants in the gene may be sex-specific risk factors in the development of schizophrenia. 15452587 2005