CD14, CD14 molecule, 929

N. diseases: 551; N. variants: 8
Disease: Allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE Sensitivity to House Dust Mites Allergens with Atopic Asthma and Its Relationship with CD14 C(-159T) Polymorphism in Patients of West Bengal, India. 29045689 2018
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE This study also demonstrates that the CD14 (-159 C/T) polymorphism is a risk factor for moderate-severe allergic asthma in adult Caucasians. 29515128 2018
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE The association between genotype frequencies of the CD14 gene loci with total-IgE and eosinophil levels in atopic asthma and non-atopic asthma was evaluated by the ANOVA test method. 26365205 2016
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE Our data suggest that the CD14 TT genotype may be a genetic susceptibility marker for atopic asthma in Chinese Han children. 25966203 2015
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE We found that CD14 -159T allele, CD14 -550T allele and CD14 -159T/-550T haplotype were significantly associated with atopic asthma and allergic rhinitis groups. 24044964 2014
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE Association between gene polymorphism of CD14-159 (C/T) and allergic asthma. 21842127 2012
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 AlteredExpression disease BEFREE The IL-4Rα, IL-13, IL-13Rα1, CD14, and CTLA4 polymorphisms were selected as the best model of increased total serum IgE levels in non-atopic and atopic asthma (asthma: accuracy = 0.4726, CVC = 10/10; atopic asthma: accuracy = 0.4573, CVC = 10/10). 22376040 2012
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE Several studies have shown that promoter polymorphisms of the CD14 gene are associated with atopic asthma. 21905503 2011
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE CD14 gene polymorphism is not associated with asthma but rather with bronchial obstruction and hyperreactivity in Slovenian children with non-atopic asthma. 22015088 2011
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 Biomarker disease BEFREE This meta-analysis suggests that CD14 is a candidate gene for atopic asthma susceptibility. 21079949 2011
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 Biomarker disease BEFREE Neither TLR4 nor CD14 were associated with T1D or allergic asthma. 19148143 2009
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 Biomarker disease BEFREE TLR2 and CD14 SNPs were associated with asthma and atopic asthma respectively. 19096003 2009
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE Virus-induced wheezing has frequently been associated with IL-8 polymorphisms, whereas atopic asthma and atopy have frequently been associated with Th2 cytokine gene (CD14 and IL-13) polymorphisms on chromosome 5. 20126925 2009
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE To verify the association of transforming growth factor-beta1(TGF-beta1) (C-509T and T869C), CD14 (C-159T), IL-4 (C-590T), IL-4R (ILe50Val) and ADAM33 (S_2) gene polymorphisms with asthma severity in a sample of patients with mild, moderate and severe persistent atopic asthma. 18425216 2008
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 Biomarker disease BEFREE Our results indicate that PAl-1 and CD14 may interact to affect susceptibility to allergic asthma. 18714537 2008
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE To examine possible associations of CD14 polymorphisms with asthma susceptibility, we performed transmission disequilibrium tests (TDTs) of 137 Japanese families identified through children with atopic asthma. 17075287 2006
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE Our study demonstrates that the CD14-C159T promoter variant influences total IgE levels and also indicates that the T allele has a more profound effect on total IgE in children with atopic asthma. 16266379 2005
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.100 GeneticVariation disease BEFREE These findings provide suggestive evidence of association of the CD14 gene locus with atopic asthma in northern and northwestern Indian populations. 15378299 2004