Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE In conclusion, NAPRT-dependent NAD<sup>+</sup> biosynthesis contributes to cell metabolism and to the DNA repair process in a subset of tumors. 28507103 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 AlteredExpression group BEFREE Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors. 26675378 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 AlteredExpression group BEFREE Particularly, mutations that decrease NAPRT1 expression can predict the usefulness of Nicotinic Acid in tumor treatments with NAMPT inhibitors. 25201160 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE As a result, the therapeutic index of GMX1777 can be widended in the treatment animals bearing NAPRT1-deficient tumors by coadministration with NA. 19703994 2009