Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Plasma adiponectin and skeletal muscle AdipoR2 mRNA expression are reduced in subjects with diabetes; both are likely to contribute to the observed insulin resistance.
|
18363889 |
2008 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Role of Serum Adiponectin and Vitamin D in Prediabetes and Diabetes Mellitus.
|
28236525 |
2017 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
As the rates of obesity and diabetes increase in African Americans and Hispanics, adiponectin and its functional SNPs may aid in breast cancer risk assessment.
|
23624817 |
2013 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Adiponectin has also β cell protective effects and may prevent the development of diabetes.
|
30857216 |
2019 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association of adiponectin gene polymorphism rs266729 with type two diabetes mellitus in Iraqi population. A pilot study.
|
26051417 |
2015 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A novel heterozygous T deletion at position 186 in exon 2 of ADIPOQ, causing a frameshift at codon 62 and leading to a premature termination at codon 168 (p.Gly63ValfsX106), was found in two individuals with diabetes.
|
19178518 |
2009 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
To investigate the association of ADIPOQ variants, total and high molecular weight adiponectin (HMW) adiponectin levels with the prevalence of diabetes mellitus and coronary artery disease (CAD) diagnosed by coronary angiography in Brazilian subjects with high cardiovascular risk.
|
22459242 |
2012 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The adiponectin gene is located on chromosome 3q27, where a diabetes susceptibility locus has been mapped.
|
15047634 |
2004 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The present prospective investigation provides further evidence for a protective role of adiponectin gene variation in the risk of ischemic stroke that was independent of the presence of diabetes.
|
16990411 |
2006 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
This study establishes that low levels of adiponectin associated with obesity, the metabolic syndrome, and diabetes favor T-lymphocyte recruitment and contribute to adaptive immune response during atherogenesis.
|
17991878 |
2008 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Parental DM was associated with lower adiponectin but higher RBP4 concentrations in offspring (<i>P</i>≤0.02 for both).
|
28713075 |
2017 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
In a subset of hyperglycemic L1 mice, we observed decreased mRNA expression of AdipoR2 in liver and muscle, as well as decreased peroxisome proliferator-activated receptor (PPAR)alpha target gene expression in liver, raising the possibility that deterioration of adiponectin/AdipoR2 signaling via PPARalpha activation contributes to the progression from compensated insulin resistance to diabetes.
|
17475934 |
2007 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association between 276G/T adiponectin gene polymorphism and new-onset diabetes after kidney transplantation.
|
23985723 |
2013 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are suggested.
|
16567542 |
2006 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Murine evidence suggests that adiponectin can exert insulin-sensitising effects, plasma concentrations of adiponectin in humans correlate in most populations with insulin sensitivity, and increasingly strong evidence suggests an association between common genetic variation around the adiponectin gene and diabetes.
|
22342226 |
2012 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
The release of adiponectin was also reduced by one-third in explants from morbidly obese diabetic women while that of IL-8 was unaffected by diabetes.
|
17895880 |
2008 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Adiponectin SNP sites were investigated at +45 of exon 2 and at +276 of intron 2; these sites have been thought to be associated with diabetes or insulin resistance.
|
19484180 |
2009 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Circulating concentrations of adiponectin are lower in patients with diabetes, cardiovascular disease, and several malignancies.
|
19906806 |
2010 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
C1q tumour necrosis factor-related protein 9 and adiponectin were higher in diabetes mellitus with severe peripheral arterial disease than diabetes mellitus with mild and moderate peripheral arterial disease groups.
|
29543038 |
2018 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Macrophages from patients with diabetes mellitus were cultured in adiponectin-free or adiponectin-supplemented media and exposed to oxidized low-density lipoprotein cholesterol (OxLDL).
|
23466101 |
2013 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
The data suggest that subcutaneous adipose tissue may play an important role in modulating adiponectin expression in diabetes and obesity.
|
20651470 |
2011 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
The aim of the present study was to assess the association of low ADPN plasma levels with the presence of subclinical atherosclerosis in a Mexican-Mestizo population without history of diabetes or coronary artery disease (CAD).
|
28577872 |
2017 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Although targeting adiponectin and its receptors has been useful for treating diabetes and other metabolic-related diseases in experimental studies, current drug development based on adiponectin/adiponectin receptors for clinical applications is scarce, and there is a lack of available clinical trial data.
|
25818192 |
2015 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Adiponectin is a fat tissue-derived adipokine with beneficial effects against diabetes, cardiovascular diseases, and cancer.
|
29991592 |
2018 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
TCERG1L is associated with plasma adiponectin, a key modulator of obesity, inflammation, IR and diabetes.
|
22791750 |
2012 |