Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE The objective of the present study was to investigate the correlations between serum undercarboxylated osteocalcin (ucOC) or osteocalcin (OC) concentrations and %body fat, serum adiponectin and free-testosterone concentration, muscle strength and dose of exogenous insulin in patients with type 1 diabetes. 31050684 2019
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Patients with T1D had a lower waist/hip ratio and serum triglycerides but higher serum adiponectin than patients with T2D. 30689904 2019
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Measurements of NPB and NPW, besides leptin and adiponectin, are worth considering in the detailed prognosis of nutritional status in T1DM, primarily in the T1DM pen-treated population. 31110527 2019
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE Spontaneous IDD in the SPARC-null mice caused a dysregulation of interleukin (IL)-1β, IL6, transforming growth factor-beta (TGFβ1), and adiponectin expression. 30273227 2018
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Adiponectin Mediates Running-Restored Hippocampal Neurogenesis in Streptozotocin-Induced Type 1 Diabetes in Mice. 30333718 2018
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Forkhead box O1 (FoxO1) and adiponectin (APN) have been proposed to play an important role in the processes in NAFLD in T1DM. 30186875 2018
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE The aim of this study was to measure serum adiponectin, leptin and resistin levels and to investigate their relationships with vitamin D and other clinical and laboratory parameters in patients with type 1 diabetes. 28721140 2017
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE In the subgroup analysis stratified by disease type, the serum/plasma levels of adiponectin in T1DM, RA and SLE patients were higher than those in normal control, but not in AS patients. 28702765 2017
Diabetes Mellitus, Insulin-Dependent
0.100 GeneticVariation disease BEFREE Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study. 27871914 2017
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Compared to non-diabetics, adults with type 1 diabetes had significantly higher adiponectin, and the difference remained significant after adjusting for AER and/or eGFR (p<0.0001). 27368123 2017
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE Plasma adiponectin levels are associated with the prevalence of DN and the incidence of ESRD in patients with type 1 diabetes. 28499019 2017
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Adiponectin was higher in patients with type 1 diabetes compared to patients with type 2 diabetes, but decreased with treatment with both BIL and glargine. 28587667 2017
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE In a prospective study of pregnant women with type 1 diabetes, we measured plasma levels of adipokines known to be associated with insulin resistance: leptin, fatty acid binding protein 4 (FABP4), adiponectin (total and high molecular weight [HMW]; also known as high molecular mass), retinol binding protein 4 (RBP4) and resistin and evaluated associations with the subsequent development of pre-eclampsia. 28875223 2017
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes. 27565410 2016
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE We measured the concentrations of oxidative/inflammatory biomarkers (urinary 15-isoprostane F(2t) [IsoP], α- and γ-tocopherol, tumor necrosis factor α [TNF-α], high-sensitivity C-reactive protein [hsCRP], white blood cell [WBC] count, fibrinogen, and adiponectin) thrice during 20 years of follow-up among 454 individuals with childhood-onset type 1 diabetes (mean baseline age, 28 years and diabetes duration, 19 years). 26114833 2015
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Adiponectin has been extensively studied in the context of several aspects and risk factors of cardiovascular disease such as obesity, diabetes type I and II, coronary heart disease, hypertension, heart failure, cerebrovascular disease and smoking. 23470075 2013
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE Expression of adiponectin and its receptors in type 1 diabetes mellitus in human and mouse retinas. 23922494 2013
Diabetes Mellitus, Insulin-Dependent
0.100 GeneticVariation disease BEFREE Association of the adiponectin rs266729 C>G variant and coronary heart disease in the low risk 'Golden Years' type 1 diabetes cohort. 21208676 2011
Diabetes Mellitus, Insulin-Dependent
0.100 GeneticVariation disease BEFREE Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus. 20667095 2010
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE The relationship between parental BMI, waist-hip ratio, homeostasis model assessment of insulin resistance (HOMA-IR), leptin and adiponectin levels and age at diagnosis of Type 1 diabetes in offspring was examined. 21105490 2010
Diabetes Mellitus, Insulin-Dependent
0.100 GeneticVariation disease BEFREE Polymorphisms in the adiponectin gene (ADIPOQ) have been associated with type 2 diabetes and diabetic nephropathy in type 1 diabetes, in mostly European-derived populations. 19056609 2009
Diabetes Mellitus, Insulin-Dependent
0.100 Biomarker disease BEFREE Serum adiponectin predicts all-cause mortality and end stage renal disease in patients with type I diabetes and diabetic nephropathy. 18496510 2008
Diabetes Mellitus, Insulin-Dependent
0.100 GeneticVariation disease BEFREE The present study aims to evaluate the association of the ACDC genetic variation in T1D and diabetic nephropathy (DN). 17189871 2007
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE Adiponectin levels do not contribute to the prediction of type 1 diabetes in Ab+ relatives. 17687539 2007
Diabetes Mellitus, Insulin-Dependent
0.100 AlteredExpression disease BEFREE In a stepwise (forward followed by backward) multiple regression model only type-1 diabetes (P < 0.001) and visceral fat mass (P < 0.05) were independently associated with plasma adiponectin levels. 14675060 2004