CD27, CD27 molecule, 939

N. diseases: 154; N. variants: 6
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.030 Biomarker group BEFREE The CD27/CD70 costimulatory pathway was shown to be critical for T cell function and survival in viral infection models. 28550198 2017
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.030 Biomarker group BEFREE In mice, co-stimulation of CD8<sup>+</sup> T-cells through CD27 promotes immune activation and enhances primary, secondary, memory and recall responses towards viral infections. 28086150 2017
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.030 Biomarker group BEFREE Our data provide a novel mechanism by which LCMV avoids nAb responses and suggest that blocking the CD27-CD70 interaction may be an attractive strategy to prevent chronic viral infection. 16923852 2006