ACVRL1, activin A receptor like type 1, 94

N. diseases: 224; N. variants: 114
Disease: Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 Biomarker group BEFREE However, cutaneous ALCL regardless of ALK-1 status may be secondary to systemic lymphoma. 21366363 2011
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 GeneticVariation group BEFREE Diffuse large B-cell lymphoma (DLBCL) with plasmablastic features associated with t(2;17)(p23;q23) and characteristic granular cytoplasmic anaplastic lymphoma kinase-1 (ALK1) protein expression is a rare lymphoma subtype. 19521280 2009
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 Biomarker group BEFREE Lymphomas showing ALK1 reactivity occurred in a younger patient population (median age, 19.5 years) and were associated with improved 5-year survival rates (84%), as compared with lymphomas lacking ALK1 reactivity (median age, 68.0 years; 5-year survival rate, 35%; p = 0.008). 10555007 1999