GRAP2, GRB2 related adaptor protein 2, 9402

N. diseases: 538; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.030 Biomarker group BEFREE Of importance, mice receiving DOX with resveratrol co-administration displayed normalization in p38 MAPK activation in the heart and a restored capacity for cardiac hypertrophy in response to Ang II-induced hypertension. 29566148 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.030 Biomarker group BEFREE Our data demonstrated that p38 MAPK may be a potential therapeutic target for hypertension-related cognitive dysfunction. 27283322 2016
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.030 Biomarker group BEFREE These results suggest an important role for p38 MAPK in endothelial inflammation and dysfunction as well as providing the first evidence for p38 MAPK-dependent hypertension. 14561851 2003