GRAP2, GRB2 related adaptor protein 2, 9402

N. diseases: 538; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.050 Biomarker disease BEFREE Recombinant CC16 inhibits NLRP3/caspase-1-induced pyroptosis through p38 MAPK and ERK signaling pathways in the brain of a neonatal rat model with sepsis. 31775794 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.050 Biomarker disease BEFREE Our results suggest that MALAT1 aggravates cardiac inflammation and dysfunction in sepsis, which is achieved via interaction with miR-125b and p38 MAPK/NFκB. 29227823 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.050 AlteredExpression disease BEFREE Up-regulation of miR-135a could aggravate sepsis-induced inflammation and myocardial dysfunction via activation of p38 MAPK/NF-κB pathway. 28147298 2017
CUI: C0243026
Disease: Sepsis
Sepsis
0.050 Biomarker disease BEFREE Further studies are needed to illuminate the detailed mechanisms of JNK and p38 MAPK signaling in sepsis‑induced ARDS. 29039541 2017
CUI: C0243026
Disease: Sepsis
Sepsis
0.050 Biomarker disease BEFREE Here we investigate the role of p38 MAPK signaling in the antiviral response against HPAIV in mice as well as in human endothelial cells, the latter being a primary source of cytokines during systemic infections. 24189062 2014