CD86, CD86 molecule, 942

N. diseases: 219; N. variants: 11
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.340 Biomarker disease BEFREE Incorporation of CTLA4Ig in conditioning aided long-term remission in myeloma probably by blocking the CD28-CD86 pro-survival pathway when combined with CTLA4Ig-primed DLI. 31449833 2019
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.340 Biomarker disease BEFREE CD86 regulates myeloma cell survival. 29296880 2017
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.340 Biomarker disease BEFREE Consistent with these observations, in vivo blockade of CD28-CD80/CD86 in the Vk*MYC murine myeloma model sensitizes MM cells to chemotherapy and significantly reduces tumor burden. 24782505 2014
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.340 Biomarker disease CTD_human Circulating levels and clinical significance of soluble CD86 in myeloma patients. 16611307 2006
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.340 AlteredExpression disease BEFREE The yield as well as the pattern and intensity of Ag (HLA-DR, CD40, CD54, CD80, and CD86) expression were equivalent on DCs from BM or PB of MM patients versus normal donors. 10029575 1999