QKI, QKI, KH domain containing RNA binding, 9444

N. diseases: 61; N. variants: 3
Disease: Schizophrenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease BEFREE Moreover, we demonstrate that Gomafu binds directly to the splicing factors QKI and SRSF1 (serine/arginine-rich splicing factor 1) and dysregulation of Gomafu leads to alternative splicing patterns that resemble those observed in SZ for the archetypal SZ-associated genes DISC1 and ERBB4. 23628989 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease PSYGENET Moreover, we demonstrate that Gomafu binds directly to the splicing factors QKI and SRSF1 (serine/arginine-rich splicing factor 1) and dysregulation of Gomafu leads to alternative splicing patterns that resemble those observed in SZ for the archetypal SZ-associated genes DISC1 and ERBB4. 23628989 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease BEFREE Linkage, association and expression studies previously pointed to the human QKI, KH domain containing, RNA-binding (QKI) as a candidate gene for schizophrenia. 23321059 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease PSYGENET Linkage, association and expression studies previously pointed to the human QKI, KH domain containing, RNA-binding (QKI) as a candidate gene for schizophrenia. 23321059 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease BEFREE The human QKI gene, called quaking homolog, KH domain RNA binding (mouse), is a candidate gene for schizophrenia encoding an RNA-binding protein. 20927331 2010
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 GeneticVariation disease BEFREE These results suggest that the variants within the promoter region of QKI gene are unlikely to play a major role in susceptibility to schizophrenia in the Chinese population. 18938205 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease PSYGENET These results suggest that the variants within the promoter region of QKI gene are unlikely to play a major role in susceptibility to schizophrenia in the Chinese population. 18938205 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease BEFREE The quaking homolog, KH domain RNA binding (mouse) (QKI) is a candidate gene for schizophrenia. 19335891 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 GeneticVariation disease BEFREE The two family based studies suggest that there may be functional variants of the QKI gene that increase the susceptibility of schizophrenia in northern Sweden, whereas the case-control study suggest that splicing of the gene may be disturbed in schizophrenic patients from other geographical origins. 16342280 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease PSYGENET The two family based studies suggest that there may be functional variants of the QKI gene that increase the susceptibility of schizophrenia in northern Sweden, whereas the case-control study suggest that splicing of the gene may be disturbed in schizophrenic patients from other geographical origins. 16342280 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 AlteredExpression disease LHGDN Given the role of QKI in determination of oligodendrocyte fate, these results not only confirm oligodendrocyte-related gene expression abnormalities in schizophrenia but suggest that the physiology of glial progenitor cells may be altered in schizophrenia. 17012699 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease PSYGENET Given the role of QKI in determination of oligodendrocyte fate, these results not only confirm oligodendrocyte-related gene expression abnormalities in schizophrenia but suggest that the physiology of glial progenitor cells may be altered in schizophrenia. 17012699 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease LHGDN The two family based studies suggest that there may be functional variants of the QKI gene that increase the susceptibility of schizophrenia in northern Sweden, whereas the case-control study suggest that splicing of the gene may be disturbed in schizophrenic patients from other geographical origins. 16342280 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker disease BEFREE Given the role of QKI in determination of oligodendrocyte fate, these results not only confirm oligodendrocyte-related gene expression abnormalities in schizophrenia but suggest that the physiology of glial progenitor cells may be altered in schizophrenia. 17012699 2006