RASAL2, RAS protein activator like 2, 9462

N. diseases: 38; N. variants: 4
Disease: Triple Negative Breast Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3539878
Disease: Triple Negative Breast Neoplasms
Triple Negative Breast Neoplasms 		0.020 Biomarker disease BEFREE In conclusion, these results indicate that the miR-136/RASAL2/MET axis act as a suppressor of TNBC metastasis. 27108696 2016
CUI: C3539878
Disease: Triple Negative Breast Neoplasms
Triple Negative Breast Neoplasms 		0.020 AlteredExpression disease BEFREE RASAL2 acted independently of its RAS-GAP catalytic activity in TNBC; however, RASAL2 promoted small GTPase RAC1 signaling, which promotes mesenchymal invasion, through binding and antagonizing the RAC1-GAP protein ARHGAP24. 25384218 2014