FXR2, FMR1 autosomal homolog 2, 9513

N. diseases: 8; N. variants: 0
Disease: Fragile X Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0016667
Disease: Fragile X Syndrome
Fragile X Syndrome 		0.040 Biomarker disease BEFREE The functions of FXR1P and FXR2P and their possible roles in producing or modulating the phenotype observed in FXS are yet to be identified. 30654445 2019
CUI: C0016667
Disease: Fragile X Syndrome
Fragile X Syndrome 		0.040 Biomarker disease BEFREE Both FMRP and FXR2P regulate neurogenesis, a process affected in a number of neurological and neuropsychiatric disorders, including fragile X syndrome. 28204491 2017
CUI: C0016667
Disease: Fragile X Syndrome
Fragile X Syndrome 		0.040 Biomarker disease BEFREE Exon trapping identified two known genes from chromosome 17: FMR1L2 (the fragile X mental retardation syndrome like protein 2) and SHBG (human sex hormone-binding globulin). 9195154 1997
CUI: C0016667
Disease: Fragile X Syndrome
Fragile X Syndrome 		0.040 Biomarker disease BEFREE FXR1 and FXR2 are thus likely to play important roles in the function of FMR1 and in the pathogenesis of the Fragile X Mental Retardation Syndrome. 7489725 1995