GDF15, growth differentiation factor 15, 9518

N. diseases: 389; N. variants: 3
Disease: Septicemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE Exogenous NRG-1β could compensate for sepsis-induced diminished NRG-1 in the diaphragm and attenuate the reduction in diaphragm contractile forces and muscle fiber areas during sepsis. 30989579 2019
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE Based on the knowledge from animal studies of its involvement in multiple inflammatory processes, we will focus in this review on the current clinical data on GDF-15 as a biomarker for cardiovascular disease, kidney disease, liver disease, the metabolic syndrome, diabetes mellitus, and sepsis. 31076013 2019
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE The present study aimed to determine whether GDF‑15 participates in sepsis‑induced acute liver injury in mice. 29956733 2018
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE Therefore, this study highlights the therapeutic potential of GDF15 in the treatment of endotoxin-induced sepsis. 28432312 2017
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 AlteredExpression disease BEFREE Collectively, serum GDF-15 levels are significantly increased in critically ill patients, associated with sepsis, organ failure, and disease severity. 29180833 2017