GDF15, growth differentiation factor 15, 9518

N. diseases: 389; N. variants: 3
Disease: Acute Chest Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 Biomarker disease BEFREE Methods We measured baseline GDF-15 (Roche, Elecsys) in 4330 patients with NSTE-ACS enrolled in MERLIN-TIMI 36. 30710475 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 Biomarker disease BEFREE The way GDF-15 patterns in post-ACS patients behave on the long term is largely unknown. 31047655 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 Biomarker disease BEFREE In a pre-specified nested analysis within a randomized, double-blind trial of ezetimibe/simvastatin versus placebo/simvastatin (IMPROVE-IT [Improved Reduction of Outcomes: Vytorin Efficacy International Trial]), high-sensitivity troponin T, N-terminal pro-B-type natriuretic peptide, growth-differentiation factor-15, and high-sensitivity C-reactive protein was measured in 7,195 patients stabilized (1 month post-randomization) after ACS. 31439215 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 Biomarker disease BEFREE We aimed to assess the long-term prognostic value of GDF-15 in ACS. 31369736 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 Biomarker disease BEFREE There was a significant association between high-level GDF-15 and mortality, recurrent MI in patients with ACS. 31029521 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 AlteredExpression disease BEFREE The NPs and GDF-15 provide the strongest prognostic increment to cTn levels in ACS. 28315120 2017
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 AlteredExpression disease BEFREE GDF-15 levels may therefore be useful as part of decision support concerning long-term antithrombotic treatment in patients post-ACS. 28411246 2017
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 Biomarker disease BEFREE In conclusion, increased GDF-15 plasma concentrations at the time of PCI and stent implantation might classify high-risk patients with ACS who benefit from high-dose, highly efficient statins. 28734463 2017
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.090 GeneticVariation disease BEFREE We measured the circulating concentrations of follistatin-like 1 (FSTL1) and GDF15 in 1369 patients with ACS. 22675198 2012