|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
This review focuses on new immunotherapeutic treatment options and strategies for frontline treatment, including a brief discussion of the use of true immunotherapy, chimeric antigen receptor T-cells, for relapsed B-cell ALL, the potential for targeting CD38 in T-cell ALL, and how these approaches are facilitating the next steps to improve survival for adult patients with ALL.
|
30466749 |
2018 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We demonstrate that blasts from patients with T-ALL have robust surface CD38 surface expression and that this expression remains stable after exposure to multiagent chemotherapy.
|
29305553 |
2018 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
COL4A5 was not differentially expressed in the t(X;7)-positive sample compared to five T-ALL controls.
|
19055661 |
2009 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The t(10;11)(p13;q14-21) is a non-random translocation that occurs primarily in T cell acute lymphoblastic leukemias (T-ALL), but has also been observed in leukemias and lymphomas of diverse lineages.
|
9737689 |
1998 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In T-cell ALL with t(10;14) translocation, the HOX 11 gene is deregulated.
|
9695407 |
1998 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Previous studies described the t(10;11)(p13-14;q14-21) as a recurring translocation associated with T-cell acute lymphoblastic leukemia (ALL).
|
9365832 |
1997 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
HOX11 is identified from the breakpoint of human T cell acute lymphoblastic leukemias with t(10;14).
|
8559142 |
1995 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The t(10;14) chromosomal translocation of T-cell acute lymphoblastic leukemia joins the T-cell receptor delta gene to a region upstream of a diverged homeobox-containing gene called HOX11.
|
7905617 |
1994 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Molecular analysis of the t(10;14) chromosomal translocation found in pediatric patients with T-cell acute lymphoblastic leukemia has led to the identification of the HOX-11 (TCL-3) protooncogene.
|
7902555 |
1993 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Here we report the identification of an oligopurine/oligopyrimidine DNA in the t(10;14) breakpoint cluster region associated with T-cell acute lymphoblastic leukemia.
|
1741251 |
1992 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Comparison of the tcl-3 cDNA and its 5' genomic sequences with DNA sequences from the t(10;14) translocation breakpoints showed that this gene is structurally altered in four patients with t(10;14)(q24;q11) T-ALL.
|
1717256 |
1991 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
t(10;11)(p13-14;q14-21): a new recurrent translocation in T-cell acute lymphoblastic leukemias. Groupe Français de Cytogénétique Hématologique (GFCH).
|
1777411 |
1991 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Molecular characterization of the t(10;14) translocation breakpoints in T-cell acute lymphoblastic leukemia: further evidence for illegitimate physiological recombination.
|
2078512 |
1990 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We cloned the t(10;14) recurrent translocation from CD3-negative T-cell acute lymphoblastic leukemia cells.
|
2326274 |
1990 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.
|
2885838 |
1987 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The HLA-DR antigen was either acquired or lost in 5 of the 68 cases, terminal deoxynucleotidyl transferase was lost in 6 of 25 cases, and reactivity of the T10 antigen with monoclonal antibodies was increased in 6 of 17 cases of non-T cell ALL.
|
2946333 |
1986 |