CD38, CD38 molecule, 952

N. diseases: 473; N. variants: 7
Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.050 Biomarker disease BEFREE Activated (CD38+HLA-DR+) PD-1+ CD4 T cells are strongly associated with virus replication and disease progression in untreated HIV-1 infection, and viral persistence in individuals on ART. 31764072 2020
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.050 Biomarker disease BEFREE Strikingly, depletion of plasmacytoid dendritic cells (pDCs) prevented human CD34+CD38- early HPCs from HIV-1 infection-induced depletion and functional impairment and restored the gene expression profile of purified CD34+ HPCs in humanized mice. 28759657 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.050 Biomarker disease BEFREE Cytomegalovirus-specific responses of CD38⁺ memory T cells are skewed towards IFN-γ and dissociated from CD154 in HIV-1 infection. 24594993 2014
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.050 Biomarker disease BEFREE Importantly, CD38(+)CD8(+) T-cell expression is a clinical correlate for progression of HIV-1 infection and biological marker for immune activation. 19365854 2009
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.050 AlteredExpression disease BEFREE In HIV-1-infected patients, increased CD38 expression on CD8+ T cells is linked to immune system activation and progression of HIV-1 infection. 18581239 2008