Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.030 Biomarker phenotype BEFREE The results showed that PIG3 knockdown significantly inhibited the migration and invasion ability of NSCLC cells, and decreased paxillin, phospho-focal adhesion kinase (FAK) and phospho-Src kinase expression, while its overexpression resulted in the opposite effects. 30281878 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.030 AlteredExpression phenotype BEFREE PIG3 overexpression increases the colony formation, migration and invasion ability of HCT116 colon cancer cells. 28280421 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.030 AlteredExpression phenotype BEFREE PIG3, which functions in DNA damage repair, uses an unexpected catalytic mechanism to suppress Rho-ROCK activity and impair tumor invasion in vivo. 26464464 2016