KIF20B, kinesin family member 20B, 9585

N. diseases: 39; N. variants: 2
Disease: Bladder Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 Biomarker disease BEFREE Multiple studies indicated the oncogenic role for KIF20B in several types of tumors, including breast cancer and bladder cancer. 30805928 2019
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 Biomarker disease BEFREE In a phase I/II clinical trial, a DEPDC1- and MPHOSPH1-derived short peptide vaccine demonstrated promising efficacy in preventing bladder cancer recurrence. 29632734 2018
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 Biomarker disease BEFREE A phase I study using two peptide vaccines derived from M phase phosphoprotein 1 (MPHOSPH1) and DEP domain containing 1 (DEPDC1) demonstrated promising results for the treatment of advanced bladder cancer. 29971464 2018
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 Biomarker disease BEFREE Among genes that were significantly up-regulated in the majority of bladder cancers, we here report identification of M-phase phosphoprotein 1 (MPHOSPH1) as a candidate molecule for drug development for bladder cancer. 17409436 2007