KIF20B, kinesin family member 20B, 9585

N. diseases: 39; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE Multiple studies indicated the oncogenic role for KIF20B in several types of tumors, including breast cancer and bladder cancer. 30805928 2019
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE In a phase I/II clinical trial, a DEPDC1- and MPHOSPH1-derived short peptide vaccine demonstrated promising efficacy in preventing bladder cancer recurrence. 29632734 2018
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE A phase I study using two peptide vaccines derived from M phase phosphoprotein 1 (MPHOSPH1) and DEP domain containing 1 (DEPDC1) demonstrated promising results for the treatment of advanced bladder cancer. 29971464 2018
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE Among genes that were significantly up-regulated in the majority of bladder cancers, we here report identification of M-phase phosphoprotein 1 (MPHOSPH1) as a candidate molecule for drug development for bladder cancer. 17409436 2007