AKAP12, A-kinase anchoring protein 12, 9590

N. diseases: 99; N. variants: 8
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 AlteredExpression disease BEFREE Upregulation of AKAP12 with HDAC3 depletion suppresses the progression and migration of colorectal cancer. 29484387 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 Biomarker disease BEFREE It was shown that AURKA, MT1G, and AKAP12 had a high degree of response in colorectal cancer. 24125984 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 Biomarker disease BEFREE These results demonstrate that AKAP12 may play an important role in tumor growth suppression and the survival of human colorectal cancer. 21918680 2011
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 PosttranslationalModification disease BEFREE The purpose of this study was to establish a methylation-sensitive high resolution melting (MS-HRM) assay for the quantitative detection of AKAP12 promoter methylation and expression and the association with clinicopathological variables in human colorectal cancer. 20364105 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 PosttranslationalModification disease BEFREE AKAP12 methylation was significantly higher in the colorectal cancer samples with differentiation (p=0.03). 20227403 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 PosttranslationalModification disease BEFREE Recently, AKAP12 promoter hypermethylation was reported in gastric and colorectal cancers. 18199717 2008
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease UNIPROT