CD59, CD59 molecule (CD59 blood group), 966

N. diseases: 262; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.030 Biomarker disease BEFREE In an open label Phase 1 pilot study, we administered 3 days of oral D 100 mg and Q 1000 mg to subjects with diabetic kidney disease (N = 9; 68·7 ± 3·1 years old; 2 female; BMI:33·9 ± 2·3 kg/m<sup>2</sup>; eGFR:27·0 ± 2·1 mL/min/1·73m<sup>2</sup>). 31542391 2019
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.030 AlteredExpression disease BEFREE The levels of E-DAF and E-CD59 were significantly lower in the DMN group than non-DMN group (DAF, p < 0.01; CD59, p < 0.0001). 16837818 2006
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.030 Biomarker disease BEFREE We focused our analysis on those patients who were more likely to progress to diabetic renal disease, i.e. whose GFR fell more than expected in the normal course of ageing [1 ml x min(-1) x (1.73 m(2))(-1) per year]. 12595762 2003