CD59, CD59 molecule (CD59 blood group), 966

N. diseases: 262; N. variants: 7
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease BEFREE Further unveiling of the molecular mechanism that turns off CD59 expression in human melanoma cells will help to set-up more effective therapeutic strategies utilizing C-activating mAb in melanoma patients. 11807824 2002
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, acting as terminal regulator of C cascade, which is heterogeneously expressed in melanomas and represents the main restriction factor of C-mediated lysis of melanoma cells. 11056001 2000