UBE3C, ubiquitin protein ligase E3C, 9690

N. diseases: 21; N. variants: 5
Disease: Recurrent tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor 		0.020 AlteredExpression phenotype BEFREE Clinically, UBE3C overexpression significantly correlated with high-grade tumors (p < 0.05), poor overall survival, and early tumor recurrence. 26067607 2015
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor 		0.020 AlteredExpression phenotype BEFREE Clinically, a tissue microarray study of a cohort containing 323 HCC patients revealed that the overexpression of UBE3C in primary HCC tissues correlated with decreased survival (hazard ratio [HR] =1.657, 95% confidence interval [CI] =1.220-2.251, P=0.001) and early tumor recurrence (HR=1.653, 95% CI=1.227-2.228, P=0.001) in postoperative HCC patients. 24425307 2014