SEMA3E, semaphorin 3E, 9723

N. diseases: 184; N. variants: 8
Disease: Allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE The regulatory role of semaphorin 3E in allergic asthma. 30447428 2019
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE Semaphorin 3E Inhibits House Dust Mite-Induced Angiogenesis in a Mouse Model of Allergic Asthma. 30711489 2019
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE More important, replenishment of Sema3E by intranasal administration of exogenous Sema3E protects mice from allergic asthma by reducing eosinophilic inflammation, serum IgE level, and T helper cell 2/T helper cell 17 cytokine response. 28634005 2017
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE Chronic features of allergic asthma including airway hyper-responsiveness (AHR), inflammation, and remodeling were studied in Sema3E-deficient mice. 29228740 2017
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE Together, these findings identify Sema3E as a novel regulatory molecule in allergic asthma that acts upstream of proallergic events and suggest that targeting this molecule could be a novel approach to treat allergic asthma. 28108561 2017