HDAC9, histone deacetylase 9, 9734

N. diseases: 340; N. variants: 73
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.030 AlteredExpression group BEFREE We hypothesized that HDAC inhibition (HDACi) decreased transcriptional activity of glucocorticoid receptor (GR), which ameliorates hypertension and hyperglycemia in patients with CS. 28928236 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.030 Biomarker group BEFREE These results indicate that dysregulation of class I and class II HDAC protein is closely associated with chronic hypertension. 28567090 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.030 GeneticVariation group BEFREE SNP, rs12155400, in the histone deacetylase 9 gene (HDAC9) on chromosome 7, was associated with retinopathy in analysis of participants without hypertension, -1.3±0.23 (beta ± standard error), p = 6.6×10(-9). 23393555 2013