HDAC4, histone deacetylase 4, 9759

N. diseases: 256; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior
0.030 AlteredExpression phenotype BEFREE Histone Deacetylase 4 Downregulation Elicits Post-Traumatic Psychiatric Disorders through Impairment of Neurogenesis. 31169064 2019
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior
0.030 AlteredExpression phenotype BEFREE Such an abnormal behavior was completely rescued by the expression of human homologue of AHO-3, indicating that the molecular function of AHO-3 is highly conserved between nematode and human. 22512337 2012
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior
0.030 GeneticVariation phenotype BEFREE Haploinsufficiency of HDAC4 causes brachydactyly mental retardation syndrome, with brachydactyly type E, developmental delays, and behavioral problems. 20691407 2010