|
Liver carcinoma
|
0.380 |
Biomarker
|
disease |
BEFREE |
The FoxM1-KIAA0101 axis might be applied as a potential prognostic biomarker and therapeutic target for HCC.
|
31293655 |
2019 |
|
Liver carcinoma
|
0.380 |
Biomarker
|
disease |
BEFREE |
KIAA0101 tv2 has a potential to work as a therapeutic drug targeting the KIAA0101 tv1 in HCC.
|
28410205 |
2017 |
|
Liver carcinoma
|
0.380 |
Biomarker
|
disease |
CTD_human |
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
|
28284560 |
2017 |
|
Liver carcinoma
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
KIAA0101 mRNA was over-expressed in the HCC group compared to the control groups.
|
26968109 |
2016 |
|
Liver carcinoma
|
0.380 |
Biomarker
|
disease |
BEFREE |
KIAA0101 tv1 may function as a regulator, promoting cell survival in HCC through regulating the function of p53.
|
22576474 |
2012 |
|
Liver carcinoma
|
0.380 |
AlteredExpression
|
disease |
LHGDN |
NS5ATP9 is a NS5A up-regulation gene which may play a role in the pathogenesis of HCV-associated hepatocellular carcinoma.
|
18068894 |
2008 |
|
Liver carcinoma
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
NS5ATP9 is a NS5A up-regulation gene which may play a role in the pathogenesis of HCV-associated hepatocellular carcinoma.
|
18068894 |
2008 |
|
Liver carcinoma
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
KIAA0101 mRNA was overexpressed in 131 (61%) HCCs, and protein was detected in 105 (64%).
|
17875765 |
2007 |
|
Liver carcinoma
|
0.380 |
Biomarker
|
disease |
BEFREE |
Here we aimed to investigate levels of PAF, lyso-PAF (the PAF precursor), phospholipase A(2) (PLA(2), the enzymatic activity generating lyso-PAF), acetylhydrolase activity (AHA, the PAF degrading enzyme) and PAF receptor (PAF-R) transcripts in cirrhotic liver and hepatocellular carcinoma (HCC).
|
16718768 |
2006 |
|
Liver carcinoma
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Western blot showed KIAA0101 protein expression was down-regulated in HCC tissues as compared with their counterpart non-cancerous liver tissues in 25 out of 30 cases.
|
16646990 |
2006 |
|
Liver carcinoma
|
0.380 |
AlteredExpression
|
disease |
LHGDN |
Western blot showed KIAA0101 protein expression was down-regulated in HCC tissues as compared with their counterpart non-cancerous liver tissues in 25 out of 30 cases.
|
16646990 |
2006 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In nutshell, our result revealed that miR-197-5p acts as an oncosuppressor miRNA in fibrosarcoma through target regulation of KIAA0101, which can be exploited for developing RNA-based therapeutic strategies for the cure of this malignancy.
|
31001891 |
2019 |
|
White Blood Cell Count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
In nutshell, our result revealed that miR-197-5p acts as an oncosuppressor miRNA in fibrosarcoma through target regulation of KIAA0101, which can be exploited for developing RNA-based therapeutic strategies for the cure of this malignancy.
|
31001891 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Numbers and proportions (population-attributable fractions, PAF) of cancer cases attributable to these factors in Germany were calculated by sex and age groups for ages 35 to 84 years based on population projections, national cancer incidence, exposure data, and published risk estimates.
|
30236218 |
2018 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Numbers and proportions (population-attributable fractions, PAF) of incident cancer cases in Germany in 2018 attributable to these factors were estimated by sex and age groups for ages 35 to 84 years using population projections, national cancer incidence and exposure data, and published risk estimates.
|
30236216 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The PAF concentration in peripheral and tumour site blood was determined by ELISA.
|
30340558 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
PAF also induced tumor cell apoptosis and autophagy, while phenylalanine had no effect on apoptosis or autophagy.
|
29436067 |
2018 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Numbers and proportions (population-attributable fractions, PAF) of incident cancer cases in Germany in 2018 attributable to these factors were estimated by sex and age groups for ages 35 to 84 years using population projections, national cancer incidence and exposure data, and published risk estimates.
|
30236216 |
2018 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Numbers and proportions (population-attributable fractions, PAF) of cancer cases attributable to these factors in Germany were calculated by sex and age groups for ages 35 to 84 years based on population projections, national cancer incidence, exposure data, and published risk estimates.
|
30236218 |
2018 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Platelet-activating factor (PAF) receptor as a promising target for cancer cell repopulation after radiotherapy.
|
28134937 |
2017 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Platelet-activating factor (PAF) receptor as a promising target for cancer cell repopulation after radiotherapy.
|
28134937 |
2017 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Overall, KIAA0101 appears to be a key promoter of RCC malignancy induced by EPO, which provide mechanistic insights into KIAA0101 functions, and pave the road to develop new therapeutics for treatment of cancer-related and chemotherapy-induced anemia in patients with RCC.
|
26575329 |
2016 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Here we identify PCNA-associated factor (PAF) as a key molecule that controls cancer cell stemness.
|
26843124 |
2016 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Here we identify PCNA-associated factor (PAF) as a key molecule that controls cancer cell stemness.
|
26843124 |
2016 |