TRIM66, tripartite motif containing 66, 9866

N. diseases: 26; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Furthermore, TRIM66 knockdown markedly inhibited tumor growth in a mouse xenograft model. 31472144 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 AlteredExpression group BEFREE High expression of TRIM66 was positively correlated with tumor stage, lymph node metastasis and distant metastasis, whereas not correlated with age and sex of HCC patients. 30915743 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Additionally, in vivo experiments using a xenograft tumor model showed that TRIM66 knockdown blunted the tumorigenicity of HCC cells associated with downregulation of β-catenin expression. 30710548 2019