MFN2, mitofusin 2, 9927

N. diseases: 334; N. variants: 75
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.220 AlteredExpression disease BEFREE Therapy with 2% H<sub>2</sub> increased PaO<sub>2</sub>/FiO<sub>2</sub> ratios, MMP and ATP levels, RCR, complex I activity and MFN2 expression but decreased histological score and Drp1 levels in the presence of sepsis. 30380511 2018
CUI: C0243026
Disease: Sepsis
Sepsis 		0.220 Biomarker disease BEFREE Taken together, these data indicate a critical role of Mfn2 in CD4<sup>+</sup> T cell apoptosis in sepsis and the underlying mechanism of autophagy deficiency. 29358849 2017
CUI: C0243026
Disease: Sepsis
Sepsis 		0.220 Biomarker disease RGD Abnormal mitochondrial fusion-fission balance contributes to the progression of experimental sepsis. 24720571 2014