MFN2, mitofusin 2, 9927

N. diseases: 334; N. variants: 75
Disease: Renal cyst ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3887499
Disease: Renal cyst
Renal cyst 		0.010 Biomarker phenotype BEFREE In cell culture models and mice with kidney-specific PC2 knockout, knockdown of MFN2 rescued defective mitochondrial Ca<sup>2+</sup> transfer and diminished cell proliferation in kidney cysts. 31064883 2019