MVP, major vault protein, 9961

N. diseases: 172; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 Biomarker disease BEFREE Silencing of gp96 causes severe compromise in human multiple myeloma cell growth through inhibiting Wnt-LRP-survivin pathway. 24077352 2013
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 AlteredExpression disease BEFREE Systematic analysis of expression of WNT, FZD, LRP and TCF gene families demonstrated that numerous Wnt-signalling components were expressed in human osteoclasts from patients with MM. 19961481 2010
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 AlteredExpression disease LHGDN Induction of integrin beta1 expression in bone marrow cells after chemotherapy correlates with the overexpression of lung resistance protein and poor outcome in patients with multiple myeloma. 18615555 2008
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 Biomarker disease BEFREE MDR1, MRP1 and LRP have been identified as important adverse prognostic factors in AML, T-ALL and MM. 10809991 2000