FGF19, fibroblast growth factor 19, 9965

N. diseases: 123; N. variants: 0
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.220 Biomarker disease BEFREE This view is consistent with known physiological role of ACOX1 in yielding precursors of specialized proresolving mediators (SPM) and with characteristics of aging and related disorders including reduced PGC1-<i>α</i> function and improvement by strategies rising ACOX1 (via hormonal gut FGF19 and nordihydroguaiaretic acid in metabolic syndrome and diabetes conditions) and SPM (neurodegenerative disorders, atherosclerosis, and stroke). 29765501 2018
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.220 Biomarker disease BEFREE FGF19 is a promising therapeutic target for the metabolic syndrome and cholestatic diseases, but enthusiasm for its use has been tempered by FGF19-mediated induction of proliferation and hepatocellular carcinoma. 28178326 2017
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.220 Biomarker disease CTD_mouse The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis. 28673684 2017