KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs560890523
rs560890523 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs560890523
rs560890523 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins
CUI: C0686619
Disease: Secondary malignant neoplasm of lymph node
Secondary malignant neoplasm of lymph node 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs560890523
rs560890523 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2017 2017
dbSNP: rs57698689
rs57698689 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins 0.48
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2017 2017
dbSNP: rs57698689
rs57698689 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins 0.48
CUI: C0686619
Disease: Secondary malignant neoplasm of lymph node
Secondary malignant neoplasm of lymph node 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		Neoplasms; Nervous System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
Childhood Kidney Wilms Tumor 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs8720
rs8720 		1.000 0.080 12 25206009 3 prime UTR variant T/C snv 0.49
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs1137188
rs1137188 		1.000 0.080 12 25206418 3 prime UTR variant G/A snv 0.49
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs1137188
rs1137188 		1.000 0.080 12 25206418 3 prime UTR variant G/A snv 0.49
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.050 0.600 5 2011 2017
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 0.750 4 2011 2017
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 1.000 3 2010 2011
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 1.000 3 2010 2011
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 1.000 3 2010 2011
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2017
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		Neoplasms 0.020 1.000 2 2014 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.020 0.500 2 2012 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.020 0.500 2 2012 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.020 1.000 2 2011 2015
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0014175
Disease: Endometriosis
Endometriosis 		Female Urogenital Diseases and Pregnancy Complications 0.020 0.500 2 2012 2019
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.020 1.000 2 2016 2016