KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs606231202
rs606231202 		1.000 0.040 12 25245355 inframe insertion -/CCA delins
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		Neoplasms 0.700 0
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.050 0.600 5 2011 2017
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 0.750 4 2011 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.040 1.000 4 2014 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.040 1.000 4 2015 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 1.000 4 2015 2019
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 1.000 3 2010 2011
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 1.000 3 2010 2011
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 1.000 3 2010 2011
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2019
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		Neoplasms 0.020 1.000 2 2014 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.020 0.500 2 2012 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.020 0.500 2 2012 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.020 1.000 2 2011 2015
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0014175
Disease: Endometriosis
Endometriosis 		Female Urogenital Diseases and Pregnancy Complications 0.020 0.500 2 2012 2019
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.020 1.000 2 2016 2016
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.020 1.000 2 2014 2019
dbSNP: rs61761074
rs61761074 		1.000 0.080 12 25244659 intron variant A/C snv 2.7E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 1.000 1 2014 2014
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.010 1.000 1 2016 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2012 2012
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4551686
Disease: Malignant neoplasm of soft tissue
Malignant neoplasm of soft tissue 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs61764370
rs61764370 		0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02
CUI: C4525302
Disease: Stage III Gallbladder Cancer AJCC v8
Stage III Gallbladder Cancer AJCC v8 		0.010 1.000 1 2016 2016