DisGeNET - a database of gene-disease associations

PSORS1C3, psoriasis susceptibility 1 candidate 3, 100130889

N. diseases: 16; N. variants: 12

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs3094188

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0010346
Disease:

Crohn Disease

0.800

GeneticVariation

GWASDB

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.

23266558

2013

dbSNP:

rs3094188

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0010346
Disease:

Crohn Disease

0.800

GeneticVariation

GWASCAT

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.

23266558

2013

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836231
Disease:

HIV-1, RESISTANCE TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836233
Disease:

AIDS, PROGRESSION TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836230
Disease:

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836230
Disease:

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836232
Disease:

ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836231
Disease:

HIV-1, RESISTANCE TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836233
Disease:

AIDS, PROGRESSION TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs3131018

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C1836232
Disease:

ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs1265181

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C0033860
Disease:

Psoriasis

0.710

GeneticVariation

GWASCAT

Genome-wide association study of psoriasis in an Egyptian population.

30921485

2019

dbSNP:

rs1265181

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C0033860
Disease:

Psoriasis

0.710

GeneticVariation

BEFREE

Extremely high significance of association was detected between rs1265181 and psoriasis (p combined < 10E--300, OR = 16.52, 95% CI: 15.28-18.44).

21208785

2011

dbSNP:

rs1265181

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C0033860
Disease:

Psoriasis

0.710

GeneticVariation

GWASCAT

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.

19169255

2009

dbSNP:

rs116805908

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0003872
Disease:

Arthritis, Psoriatic

0.700

GeneticVariation

GWASCAT

Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.

30552173

2019

dbSNP:

rs116834467

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0518015
Disease:

Hemoglobin measurement

0.700

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs887464

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0026896
Disease:

Myasthenia Gravis

0.700

GeneticVariation

GWASDB

Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08.

23055271

2012

dbSNP:

rs887466

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C4528257
Disease:

Corpuscular Hemoglobin Concentration Mean

0.700

GeneticVariation

GWASDB

Seventy-five genetic loci influencing the human red blood cell.

23222517

2012

dbSNP:

rs3094188

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0038325
Disease:

Stevens-Johnson Syndrome

0.700

GeneticVariation

GWASCAT

Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.

21801394

2011

dbSNP:

rs3094188

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0014518
Disease:

Toxic Epidermal Necrolysis

0.700

GeneticVariation

GWASCAT

Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.

21801394

2011

dbSNP:

rs1128175

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C1836230
Disease:

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs1128175

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C1836231
Disease:

HIV-1, RESISTANCE TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs1128175

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C1836233
Disease:

AIDS, PROGRESSION TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs1128175

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C1836232
Disease:

ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs1265181

Entrez Id:	100130889
Gene Symbol:	PSORS1C3

PSORS1C3

CUI:	C0042900
Disease:

Vitiligo

0.700

GeneticVariation

GWASDB

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

20526339

2010

dbSNP:

rs3130457

Entrez Id:	5460;100130889
Gene Symbol:	POU5F1;PSORS1C3

POU5F1;PSORS1C3

CUI:	C0042900
Disease:

Vitiligo

0.700

GeneticVariation

GWASDB

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

20526339

2010