SEMA3C, semaphorin 3C, 10512

N. diseases: 71; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs139811700
rs139811700
Entrez Id: 10512
Gene Symbol: SEMA3C
SEMA3C
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs76627715
rs76627715
Entrez Id: 10512
Gene Symbol: SEMA3C
SEMA3C
CUI: C0428883
Disease:
Diastolic blood pressure 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. 27841878 2017
dbSNP: rs60839105
rs60839105
Entrez Id: 10512
Gene Symbol: SEMA3C
SEMA3C
CUI: C0392885
Disease:
High density lipoprotein measurement 		T 0.700 GeneticVariation GWASCAT Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. 27036123 2016
dbSNP: rs4461841
rs4461841
Entrez Id: 10512
Gene Symbol: SEMA3C
SEMA3C
CUI: C0024530
Disease:
Malaria 		0.010 GeneticVariation BEFREE SCT and IL10 rs1800896, IL1A rs2856838, but not SEMA3C rs4461841, polymorphisms were associated with decreased risk of malaria in the controls. 29033373 2017
dbSNP: rs4461841
rs4461841
Entrez Id: 10512
Gene Symbol: SEMA3C
SEMA3C
CUI: C0343640
Disease:
African Burkitt's lymphoma 		0.010 GeneticVariation BEFREE Decreased risk of eBL was associated with IL10 rs1800896-CT (OR 0·73, 95% CI 0·50-1·07) and -CC genotypes (OR 0·53, 95% CI 0·29-0·95, p<sub>trend</sub>=0·019); IL1A rs2856838-AG (OR 0·56, 95% CI 0·39-0·81) and -AA genotype (OR 0·50, 95% CI 0·28-1·01, p<sub>trend</sub>=0·0016); and SEMA3C rs4461841-CT or -CC genotypes (OR 0·57, 95% CI 0·35-0·93, p=0·0193). 29033373 2017