CGAS, cyclic GMP-AMP synthase, 115004

N. diseases: 40; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs311671
rs311671
Entrez Id: 115004
Gene Symbol: CGAS
CGAS
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs311671
rs311671
Entrez Id: 115004
Gene Symbol: CGAS
CGAS
CUI: C0037369
Disease:
Smoking 		0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs311686
rs311686
Entrez Id: 55510;115004
Gene Symbol: DDX43;CGAS
DDX43;CGAS
CUI: C0041296
Disease:
Tuberculosis 		0.010 GeneticVariation BEFREE Taken together, our results show that the presence of the rs311686 SNP influences the course of TB significantly. 31118495 2020
dbSNP: rs311678
rs311678
Entrez Id: 115004
Gene Symbol: CGAS
CGAS
CUI: C0940937
Disease:
precancerous lesions 		0.010 GeneticVariation BEFREE In conclusion, our results indicate that the rs311678 polymorphism in the cGAS gene confers genetic susceptibility to cervical precancerous lesions. 27705945 2016
dbSNP: rs311678
rs311678
Entrez Id: 115004
Gene Symbol: CGAS
CGAS
CUI: C0343641
Disease:
Human papilloma virus infection 		0.010 GeneticVariation BEFREE Moreover, the three-way gene-environment interactions further demonstrate that the rs31</span>1678 polymorphism in cGAS can significantly decrease the risk of HPV infection and the elder at menarche. 27705945 2016