Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs77874543
rs77874543
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C3150739
Disease:
IMMUNODEFICIENCY, COMMON VARIABLE, 4 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.010 GeneticVariation BEFREE Our results point to a possible association between the rs9514828 (CT vs. CC + TT; OR = 0.74; CI 95 % = 0.57; 0.97; p = 0.022) and rs1041569 (AT vs. AA + TT; OR = 0.72; CI 95 % = 0.54; 0.95; p = 0.021) of BAFF gene and rs61756766 (CC vs. CT; OR = 2.03; CI 95 % = 1.03; 3.99; p = 0.03) of BAFF-R gene and CLL risk. 27468724 2016
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.010 GeneticVariation BEFREE The corresponding frequencies of the His159Tyr BAFF-R mutation in SLE and RA patients were 3.5% and 3%, respectively. 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C1527336
Disease:
Sjogren's Syndrome 		0.010 GeneticVariation BEFREE A BAFF receptor His159Tyr mutation in Sjögren's syndrome-related lymphoproliferation. 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C1332206
Disease:
Adult Lymphoma 		0.010 GeneticVariation BEFREE Both the SS-lymphoma and SS-nonlymphoma patient subgroups exhibited significantly higher frequencies of the His159Tyr BAFF-R mutation compared to healthy controls (8.6% of SS-lymphoma patients and 6.2% of SS-nonlymphoma patients versus 1.7% of healthy controls; P = 0.02 and P = 0.04, respectively). 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE The corresponding frequencies of the His159Tyr BAFF-R mutation in SLE and RA patients were 3.5% and 3%, respectively. 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C1850900
Disease:
Familial primary gastric lymphoma 		0.010 GeneticVariation BEFREE This study identifies an increased prevalence of the BAFF-R His159Tyr mutation in patients with SS, particularly in those with SS complicated by MALT lymphoma whose disease onset occurred at a younger age. 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0024299
Disease:
Lymphoma 		0.010 GeneticVariation BEFREE Both the SS-lymphoma and SS-nonlymphoma patient subgroups exhibited significantly higher frequencies of the His159Tyr BAFF-R mutation compared to healthy controls (8.6% of SS-lymphoma patients and 6.2% of SS-nonlymphoma patients versus 1.7% of healthy controls; P = 0.02 and P = 0.04, respectively). 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C1332979
Disease:
Childhood Lymphoma 		0.010 GeneticVariation BEFREE Both the SS-lymphoma and SS-nonlymphoma patient subgroups exhibited significantly higher frequencies of the His159Tyr BAFF-R mutation compared to healthy controls (8.6% of SS-lymphoma patients and 6.2% of SS-nonlymphoma patients versus 1.7% of healthy controls; P = 0.02 and P = 0.04, respectively). 26097183 2015
dbSNP: rs61756766
rs61756766
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0242647
Disease:
Mucosa-Associated Lymphoid Tissue Lymphoma 		0.010 GeneticVariation BEFREE This study identifies an increased prevalence of the BAFF-R His159Tyr mutation in patients with SS, particularly in those with SS complicated by MALT lymphoma whose disease onset occurred at a younger age. 26097183 2015
dbSNP: rs77874543
rs77874543
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0243026
Disease:
Sepsis 		0.010 GeneticVariation BEFREE Interestingly, TLR4-D299G, TLR4-T399I and BAFFR-P21R carriage was associated with a lower risk of ICU-acquired sepsis. 25454804 2015
dbSNP: rs77874543
rs77874543
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
CUI: C0036690
Disease:
Septicemia 		0.010 GeneticVariation BEFREE Interestingly, TLR4-D299G, TLR4-T399I and BAFFR-P21R carriage was associated with a lower risk of ICU-acquired sepsis. 25454804 2015