FOXP4, forkhead box P4, 116113

N. diseases: 30; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0600139
Disease:
Prostate carcinoma 		T 0.720 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322 2019
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0600139
Disease:
Prostate carcinoma 		0.720 GeneticVariation BEFREE The cumulative effects test of risk alleles (rs rs1983891, rs339331, rs16901966, rs1447295 and rs10090154) showed an increasing risk to PCa in a frequency-dependent manner (ptrend=0.001), and men with more than 3 risk alleles had the most significant susceptibility to PCa (OR=1.99, p=0.001), compared with those who had one risk allele (OR=1.17, p=0.486). 26537068 2016
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.720 GeneticVariation BEFREE The cumulative effects test of risk alleles (rs rs1983891, rs339331, rs16901966, rs1447295 and rs10090154) showed an increasing risk to PCa in a frequency-dependent manner (ptrend=0.001), and men with more than 3 risk alleles had the most significant susceptibility to PCa (OR=1.99, p=0.001), compared with those who had one risk allele (OR=1.17, p=0.486). 26537068 2016
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0600139
Disease:
Prostate carcinoma 		0.720 GeneticVariation BEFREE We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer. 22662242 2012
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.720 GeneticVariation BEFREE We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer. 22662242 2012
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0600139
Disease:
Prostate carcinoma 		T 0.720 GeneticVariation GWASCAT Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. 20676098 2010
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		T 0.720 GeneticVariation GWASDB Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. 20676098 2010
dbSNP: rs3800283
rs3800283
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs1114167294
rs1114167294
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0232466
Disease:
Feeding difficulties 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs1114167294
rs1114167294
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0018818
Disease:
Ventricular Septal Defects 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs1114167294
rs1114167294
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0431527
Disease:
Laryngeal hypoplasia 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs1114167294
rs1114167294
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0557874
Disease:
Global developmental delay 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs867245225
rs867245225
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE We genotyped five single-nucleotide polymorphism (SNP): rs13385191 (chromosome 2p24), rs12653946 (5p15), rs1983891 (6p21), rs339331 (6p22), and rs9600079 (13q22), in 7,956 prostate cancer cases and 8,148 controls from a series of nested case-control studies within the National cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3). 22056501 2012
dbSNP: rs1983891
rs1983891
Entrez Id: 116113
Gene Symbol: FOXP4
FOXP4
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE We genotyped five single-nucleotide polymorphism (SNP): rs13385191 (chromosome 2p24), rs12653946 (5p15), rs1983891 (6p21), rs339331 (6p22), and rs9600079 (13q22), in 7,956 prostate cancer cases and 8,148 controls from a series of nested case-control studies within the National cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3). 22056501 2012