ADRB2, adrenoceptor beta 2, 154

N. diseases: 387; N. variants: 17
Disease: Cystic Fibrosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042713
rs1042713
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0010674
Disease:
Cystic Fibrosis 		0.020 GeneticVariation BEFREE When we used the dominant model, the MBL2 allele rs11003125 (MBL2-550; p = 0.022, Odds Ratio (OR) 2.87, 95% CI 1.14-7.27) was significantly associated with CF patients as risk factor, and the ADRB2 allele rs1042713 (p.Arg16Gly; p = 0.005, Odds Ratio (OR) 0.37, 95% CI 0.19-0.75) was significantly associated with CF patients as protect factor. 29703608 2018
dbSNP: rs1042713
rs1042713
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0010674
Disease:
Cystic Fibrosis 		0.020 GeneticVariation BEFREE There was an association between the Arg16Gly and Gln27Glu polymorphisms in ADRB2 gene with CF´s severity and bronchodilator response. 22950544 2012
dbSNP: rs1042714
rs1042714
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0010674
Disease:
Cystic Fibrosis 		0.020 GeneticVariation BEFREE There was an association between the Arg16Gly and Gln27Glu polymorphisms in ADRB2 gene with CF´s severity and bronchodilator response. 22950544 2012
dbSNP: rs1042714
rs1042714
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0010674
Disease:
Cystic Fibrosis 		0.020 GeneticVariation BEFREE Within the CF group, the Glu(27)Glu/Gln(27)Glu group had higher D(M)/V(C) and SaO(2) when compared to the Gln(27)Gln group at baseline (p < 0.05). 21703359 2011