ADRB2, adrenoceptor beta 2, 154

N. diseases: 387; N. variants: 17
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042714
rs1042714
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE As there is a high prevalence of obesity in Tonga, we aimed to determine the distribution of the beta2 adrenoceptor gene Gln(27)Glu polymorphism and to assess its relevance to obesity and to Type II diabetes, known to be prevalent in that population. 12605574 2003
dbSNP: rs1042714
rs1042714
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE However, the Glu27Gln polymorphism had no impact on either BMI or type 2 diabetes in a Taiwanese population. 12390345 2002
dbSNP: rs1042714
rs1042714
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE The aim of this study was to investigate whether polymorphisms in the beta(2)-adrenergic receptor gene (5'LC-Arg19Cys, Arg16Gly, Gln27Glu) are associated with hypertension in patients with or without type 2 diabetes and with the blood pressure levels in normotensive sib pairs. 11358945 2001
dbSNP: rs1042714
rs1042714
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes. 11380082 2001
dbSNP: rs1042713
rs1042713
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 GeneticVariation BEFREE The purpose of the present study was to evaluate the influence of the Arg16Gly variant allele of B2AR on insulin secretion in patients with type 2 diabetes. 14693408 2004
dbSNP: rs1042713
rs1042713
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 GeneticVariation BEFREE The Arg16Gly polymorphism was independently associated with age of onset in type 2 diabetes (P = 0.017). 12390345 2002
dbSNP: rs1042713
rs1042713
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 GeneticVariation BEFREE The aim of this study was to investigate whether polymorphisms in the beta(2)-adrenergic receptor gene (5'LC-Arg19Cys, Arg16Gly, Gln27Glu) are associated with hypertension in patients with or without type 2 diabetes and with the blood pressure levels in normotensive sib pairs. 11358945 2001
dbSNP: rs201777403
rs201777403
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE The DIO2 Thr92Ala variant does not confer an increased risk of T2D, obesity, or insulin resistance. 17077128 2007