Disease: Primary malignant neoplasm of lung ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6068816
rs6068816
Entrez Id: 1591
Gene Symbol: CYP24A1
CYP24A1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE This study revealed that rs1065852, rs2043449, rs2762s934, and rs6068816 of CYPs were associated with LC susceptibility in the Northwestern Chinese Han population; CYP2D6 and CYP20A1 were overexpressed and correlated with prognosis of LC. 31264381 2019
dbSNP: rs6068816
rs6068816
Entrez Id: 1591
Gene Symbol: CYP24A1
CYP24A1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Overall, these findings indicated that CYP24A1 polymorphism rs6068816 could be significantly associated with susceptibility of lung cancer in Chinese female nonsmokers. 30724597 2019
dbSNP: rs4809957
rs4809957
Entrez Id: 1591
Gene Symbol: CYP24A1
CYP24A1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE We found genome-wide significant (P < 5.0 × 10(-8)) evidence for three additional lung cancer susceptibility loci at 10p14 (rs1663689, close to GATA3, P = 2.84 × 10(-10)), 5q32 (rs2895680 in PPP2R2B-STK32A-DPYSL3, P = 6.60 × 10(-9)) and 20q13.2 (rs4809957 in CYP24A1, P = 1.20 × 10(-8)). 22797725 2012