rs11190140
NKX2-3;LINC01475
Crohn Disease
0.810
GeneticVariation
BEFREE
For rs11190140 polymorphism (C/T) and CD risk, the risk estimate for the allele contrast was OR = 1.201 (1.136-1.269).
24473197 2014
rs11190140
NKX2-3;LINC01475
Crohn Disease
T
0.810
GeneticVariation
GWASCAT
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
18587394 2008
rs11190140
NKX2-3;LINC01475
Crohn Disease
T
0.810
GeneticVariation
GWASDB
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
18587394 2008
rs11190141
NKX2-3;LINC01475
Crohn Disease
C
0.800
GeneticVariation
GWASDB
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
22412388 2012
rs11190141
NKX2-3;LINC01475
Crohn Disease
C
0.800
GeneticVariation
GWASCAT
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
22412388 2012
rs11190140
NKX2-3;LINC01475
Ulcerative Colitis
T
0.800
GeneticVariation
GWASDB
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
20228799 2010
rs11190140
NKX2-3;LINC01475
Ulcerative Colitis
T
0.800
GeneticVariation
GWASCAT
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
20228799 2010
rs11190141
NKX2-3;LINC01475
Monocyte count procedure
T
0.700
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252 2016
rs11190141
NKX2-3;LINC01475
Monocyte count result
T
0.700
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252 2016
rs10883371
NKX2-3;LINC01475
Primary sclerosing cholangitis
0.700
GeneticVariation
GWASDB
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.
23603763 2013
rs11190140
NKX2-3;LINC01475
Multiple Sclerosis
0.700
GeneticVariation
GWASDB
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
22190364 2011
rs11190140
NKX2-3;LINC01475
Asthma
0.700
GeneticVariation
GWASDB
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
21150878 2011
rs11190140
NKX2-3;LINC01475
Inflammatory Bowel Diseases
0.010
GeneticVariation
BEFREE
We speculate that the rs11190140 may regulate NKX2-3 expression and have a role in IBD pathogenesis.
21803625 2012
rs11190140
NKX2-3;LINC01475
Irritable Bowel Syndrome
0.010
GeneticVariation
BEFREE
NKX2-3 variant rs11190140 is associated with IBD and alters binding of NFAT.
21803625 2012
rs888208
×
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
Ulcerative Colitis
0.010
GeneticVariation
BEFREE
Two SNPs (rs10883365 and rs888208 ) were significantly associated with UC (p = 7.79 × 10(-4), odds ratio [OR] = 1.54 [95% confidence interval (95% CI) 1.20-1.99], p = 7.70 × 10(-3), OR = 1.41 [95% CI 1.10-1.81], respectively) and 1 SNP (rs10883365) was associated with CD (p = 0.0366, OR = 1.29 [95% CI 1.02-1.63]).
21514341 2011
rs888208
×
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
Crohn Disease
0.010
GeneticVariation
BEFREE
Two SNPs (rs10883365 and rs888208 ) were significantly associated with UC (p = 7.79 × 10(-4), odds ratio [OR] = 1.54 [95% confidence interval (95% CI) 1.20-1.99], p = 7.70 × 10(-3), OR = 1.41 [95% CI 1.10-1.81], respectively) and 1 SNP (rs10883365) was associated with CD (p = 0.0366, OR = 1.29 [95% CI 1.02-1.63]).
21514341 2011
rs888208
×
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
Celiac Disease
0.010
GeneticVariation
BEFREE
We aimed to study the implication of five polymorphisms in these genes in CD susceptibility: rs10883365 and rs888208 in the NKX2-3 gene, rs2241880 in ATG16L1, and rs10065172 and rs4958847 in IRGM.
19683022 2009