DCK, deoxycytidine kinase, 1633

N. diseases: 102; N. variants: 6
Disease: Leukemia, Myelocytic, Acute ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4643786
rs4643786
Entrez Id: 1633
Gene Symbol: DCK
DCK
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		0.010 GeneticVariation BEFREE DCK rs4643786 may serve as an independent predictor of drug response and AML outcome. 27548009 2016
dbSNP: rs67437265
rs67437265
Entrez Id: 1633
Gene Symbol: DCK
DCK
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		0.010 GeneticVariation BEFREE rs4643786 showed strong linkage disequilibrium with rs67437265. rs4643786 CT heterozygotes showed significantly higher complete remission rate (p = 0.028), superior overall survival (p = 0.006) and relapse-free survival (p = 0.020) than wild-type TT homozygotes. rs4643786 polymorphism was an independent predictor for AML prognosis. 27548009 2016