DOCK1, dedicator of cytokinesis 1, 1793

N. diseases: 58; N. variants: 8
Disease: Multiple congenital anomalies ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model. 27662902 2017
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation. 26527617 2016
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Dock-family exchange factors in cell migration and disease. 25022758 2014
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. 20829512 2010
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway. 18591431 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. 18820033 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. 18332221 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. 17670792 2007
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR GEF what? Dock180 and related proteins help Rac to polarize cells in new ways. 17765544 2007
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR A role for acetylcholine receptors in the fusion of chick myoblasts. 3372592 1988