Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12461110
rs12461110
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 26414677 2015
dbSNP: rs12461110
rs12461110
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT A genome-wide association study of early menopause and the combined impact of identified variants. 23307926 2013
dbSNP: rs12461110
rs12461110
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASDB A genome-wide association study of early menopause and the combined impact of identified variants. 23307926 2013
dbSNP: rs12461110
rs12461110
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASDB Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. 22267201 2012
dbSNP: rs12461110
rs12461110
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. 22267201 2012
dbSNP: rs12461110
rs12461110
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C0005612
Disease:
Birth Weight 		A 0.700 GeneticVariation GWASCAT Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. 31043758 2019
dbSNP: rs299163
rs299163
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2547274
rs2547274
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C1629609
Disease:
Age at menopause 		G 0.700 GeneticVariation GWASCAT Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 26414677 2015
dbSNP: rs1363758
rs1363758
Entrez Id: 204801
Gene Symbol: NLRP11
NLRP11
CUI: C0010346
Disease:
Crohn Disease 		0.010 GeneticVariation BEFREE Four single nucleotide polymorphisms (SNPs) in NLRP3 had P values < 0.05 and are in high linkage disequilibrium (LD) with each other (r(2) > 0.90 for all four SNPs). rs4925648 and rs10925019 were the most strongly associated with CD susceptibility (P = 0.001, odds ratio (OR) 1.62, 95% CI 1.2-2.18; and P = 6.5 x 10(-4), OR 1.65, 95% CI 1.23-2.19, respectively). rs1363758 located in NLRP11 was associated with CD susceptibility [P = 0.002 (1.64, 1.19-2.25)], which was weakly confirmed in an independent case-cohort collection on joint analysis [P = 0.05, (1.28, 1-1.64)]. 20403135 2010