ESR2, estrogen receptor 2, 2100

N. diseases: 528; N. variants: 56
Disease: Hepatitis C ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1256049
rs1256049
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0019196
Disease:
Hepatitis C 		0.010 GeneticVariation BEFREE Furthermore, a significant multiplicative interaction between the combined rs1256049 and rs4986938 genotypes was found to decrease HCV infection risk (adjusted OR=0.583, P=3.000×10(-4)). 25261585 2014
dbSNP: rs4986938
rs4986938
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0019196
Disease:
Hepatitis C 		0.010 GeneticVariation BEFREE We provide here the first report that rs498</span>6938 in the ESR2 gene played a potential sex-specific role in the etiology of HCV infection</span> in a high-risk Chinese Han population, suggesting that ESR2 is a candidate susceptibility gene for HCV infection and viral clearance. 25261585 2014
dbSNP: rs944459
rs944459
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0019196
Disease:
Hepatitis C 		0.010 GeneticVariation BEFREE We performed logistic regression analysis to explore the associations between rs1256049, rs4986938 and rs944459 polymorphisms of the estrogen receptor 2 gene (ESR2) and HCV infection outcomes. 25261585 2014